SMQ1 outbound queue in RUNNING status doing nothing

Hello Experts,

We have an outbound queue - "R3AI_MATERIAL" in CRM system RUNNIING status doing nothing and finally failing.

We have a dump in ECC with TIME OUT error -

We have registered R3A* queue in SMQR of CRM.

We have enough resources in both CRM and ECC

ST22 TIME_OUT dump - Termination occured in ABAP program SAPLERFC in ARFC_DEST_SHIP

Any suggestions to check?

Thanks,

Subbu