NW RFC and multi-threading.

I am currently in the process of migrating a C++ application from using Classic RFC to NW RFC. I have a multi-threading question from Note 513386 and Using Multi Threading - Components of SAP Communication Technology - SAP Library (both about JCo but look relevant) it seems that you cannot execute (call RfcInvoke) for multiple concurrent functions on the same connection. Does this apply just to RfcInvoke or all calls related to a Function (eg, RfcCreateFunction, RfcDestroyFunction, ...).

Thanks,

Simon